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New polyetherurethanes based on cellulose derivative for biomedical applications

S. VLAD1,* , D. FILIP1, D. MACOCINSCHI1, I. SPIRIDON1, A. NISTOR1, L. M. GRADINARU1, V. E. MUSTEATA1

Affiliation

  1. Institute of Macromolecular Chemistry “Petru Poni”, Aleea Grigore Ghica Voda 41A, 700487, Iasi, Romania

Abstract

This study present new polyetherurethanes (PEU) based on cellulose derivative, allowing for their application for medical devices. The polyurethane samples were synthesized from polytetramethyleneetherglycol (PTMEG), as macrodiol, 1,6-hexamethylene diisocyanate (HDI), 4,4’-methylene bis(cyclohexyl isocyanate) (HMDI), isophorone diisocyanate (IPDI), as diisocyanate components and hydroxypropyl cellulose (HPC) as chain extender, by the one-shot process without catalyst. The properties of these materials, such as water vapours sorption capacity, contact angles, thermal, mechanical and dielectrical behaviour have been evaluated with respect to their structure. By careful selection of polyurethane composition it is possible to design a range of polymers, which may have great potential in tissue engineering applications..

Keywords

Cellulose derivative, Hydrophilicity, Polyetherurethane, Tissue engineering.

Citation

S. VLAD, D. FILIP, D. MACOCINSCHI, I. SPIRIDON, A. NISTOR, L. M. GRADINARU, V. E. MUSTEATA, New polyetherurethanes based on cellulose derivative for biomedical applications, Optoelectronics and Advanced Materials - Rapid Communications, 4, 3, March 2010, pp.407-414 (2010).

Submitted at: Jan. 26, 2010

Accepted at: March 12, 2010