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Conceptual multimodal optical approach for diagnosis of foot ulcers in diabetic patients

D. SAVASTRU1, S. MICLOS1, S. DONTUa1, G. INCEU2,3, C. BONDOR2,3

Affiliation

  1. National Institute of R&D for Optoelectronics - INOE 2000, 409 Atomistilor St., Magurele, Ilfov, RO-077125, Romania
  2. “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj, RO-400012, Romania
  3. Medical Center for Podiatry, 10 Iuliu Moldovan St., Cluj-Napoca, Cluj, RO-400348, Romania

Abstract

A novel technology for diagnosing foot ulcers is being proposed. There exists an urgent need for a clinical tool capable of probing multiple markers involved in foot ulcer formation and development, such as oxygen perfusion, blood flow, and vascular structure, at both epithelial and muscle layers of the foot. Currently, there are no single modality instruments capable of performing comprehensive measurements at the both muscle and epithelium to predict ulcer formation. To address this issue, we envision the use of combined near-infrared spectroscopy (NIRS) and Optical Coherence Tomography (OCT) within the same instrument with the goal of deriving complementary information related to foot ulcer formation and therapy progression. The combination of these two techniques will provide a unique marker that may enable early prediction and monitoring of diabetic foot ulcers..

Keywords

OCT, Near-infrared spectroscopy, Foot ulcers.

Citation

D. SAVASTRU, S. MICLOS, S. DONTUa, G. INCEU, C. BONDOR, Conceptual multimodal optical approach for diagnosis of foot ulcers in diabetic patients, Optoelectronics and Advanced Materials - Rapid Communications, 10, 11-12, November–December 2016, pp.893-898 (2016).

Submitted at: Sept. 17, 2016

Accepted at: Nov. 25, 2016