"

Cookies ussage consent

Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our site without changing the browser settings you grant us permission to store that information on your device.

CdTe/CdSe quantum dots as a fluorescent probe for kanamycin determination in the pharmaceutical formulation and human serum

YONGQIANG MAO1,2, NA LI2, YE HAN1, ZHIJIANG ZHOU1,*

Affiliation

  1. School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
  2. College of Science, Liaoning Technical University, Fuxin 123000, China

Abstract

A new method for the determination of kanamycin (KANA) was developed based on enhancing the fluorescence intensity of thioglycollic acid (TGA) modified CdTe/CdSe quantum dots (QDs) by KANA. Under optimal conditions, the fluorescence intensity was proportional to the concentration of KANA between 1.0 to 10.0 μg mL-1 with a correlation coefficient of 0.9981 and a detection limit of 25 ng mL1. Moreover, the proposed method was successfully applied to the determination of KANA in the pharmaceutical formulation and human serum, and the results w ere satisfactory. In addition, the reaction mechanism was also discussed in detail..

Keywords

CdTe/CdSe Quantum dots Kanamycin Fluorescence enhancement Determination.

Citation

YONGQIANG MAO, NA LI, YE HAN, ZHIJIANG ZHOU, CdTe/CdSe quantum dots as a fluorescent probe for kanamycin determination in the pharmaceutical formulation and human serum, Optoelectronics and Advanced Materials - Rapid Communications, 6, 9-10, September-October 2012, pp.879-882 (2012).

Submitted at: Jan. 30, 2012

Accepted at: Sept. 20, 2012