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A. KRAFČÍK1, M. BABINCOVÁ1, P. BABINEC1,*
A novel magnetic cell, drug, or gene targeting system utilizing high gradient magnetic separation principles was proposed and analyzed theoretically. The system is based on four wires carrying high electric current for a short time, creating a quadrupolar magnetic field with high intensity and gradient. Analyzing trajectories of magnetic nanoparticles as well as microparticles we have found that the mean capture time is sufficiently short, and the biomedical applications of such a system are feasible.
Magnetic separation, Drug targeting, Gene therapy, Pulsed quadrupolar magnet, Magnetic particles.
A. KRAFČÍK, M. BABINCOVÁ, P. BABINEC, Theoretical analysis of magnetic particle trajectory in high-current pulsed quadrupole: implications for magnetic cell separation, drug targeting, and gene therapy, Optoelectronics and Advanced Materials - Rapid Communications, 3, 3, March 2009, pp.226-230 (2009).
Submitted at: Dec. 17, 2008
Accepted at: March 19, 2009
Optoelectronics and Advanced Materials - Rapid Communications
(2025): Impact Factor = 0.5 - Journal Citation Reports (Clarivate Analytics, 2026)
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