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2D photonic crystal based biosensor for pancreatic cancer detection

APARAJITA MALLIK1, ARCHANA SAHOO2, GAURAV KUMAR BHARTI3,*

Affiliation

  1. Department of Biotechnology Engineering, V.V.P Engineering College, Affiliated by Gujarat Technological University, India
  2. Department of Physics Rao Pahald Singh Degree College, India
  3. Department of Applied Science & Humanities, IIMT University Greater Noida Campus, India

Abstract

This paper presents a 2D photonic crystal based biosensor for numerical refractive index sensing related to pancreatic cancer. The development of pancreatic cancer begins with DNA mutations in pancreatic cells, which result in incorrect instructions enabling the cells to grow uncontrollably. As sensing devices, biosensors exhibit rapid and sensitive measurements. Therefore, they are widely used in the medical field for quick and accurate disease diagnosis. Photonic crystal biosensors are made to identify diseases like cancer, malaria and tuberculosis and others. Photonic crystal biosensors operate on the basis of a shift in the peak resonance wavelength that corresponds to minute variations in the refractive index values. A photonic biosensor has a high sensitivity and can provide results quickly. The variations in refractive index between normal and abnormal biological conditions can result in a shift in the resonance wavelength. The simulation and analysis of the design have been done using the Finite Difference Time Domain (FDTD) method.

Keywords

2D photonic crystal, Biosensor, FDTD, Pancreatic cancer, Refractive index.

Citation

APARAJITA MALLIK, ARCHANA SAHOO, GAURAV KUMAR BHARTI, 2D photonic crystal based biosensor for pancreatic cancer detection, Optoelectronics and Advanced Materials - Rapid Communications, 20, 9-10, September-October 2026, pp.421-427 (2026).

Submitted at: Dec. 12, 2025

Accepted at: Oct. 5, 2026